Non-Clinical Toxicology Lead (Principal Scientist) - Brussel

Vacancy information

Publication date:February 20 2020
Employment type:Permanent
Function Group:R&D

Function Group: R&D / Toxicologist


In their continued efforts regarding the discovery and development of groundbreaking medicines and solutions for severe immune system and CNS diseases, my client is looking for a skilled Toxicologist with experience in the non-clinical development of CNS drug candidates. This internationally active company (over 8.000 headcount and active in over 40 counties) is widely known for its scientific excellence and entrepreneurial mindset, resulting in a multitude of running drug development programs. Therefore they look for a Toxicology specialist to strengthen their existing team and take the lead on non-clinical safety issues in multiple project teams.


In this role, you will join the Non-Clinical Toxicology group within the Preclinical Development branch of their R&D structure, You will be responsible for all non-clinical safety aspects within multiple preclinical development programs. You will be able to fully focus on the strategic and scientific aspects, while delegating the necessary in-vitro and in-vivo tests to a dedicated team. In this role you will work both on small molecule (NCE), biologics (NBE) and new modality drug candidates. The focus will lie on CNS research, but occasional support on the immunology / inflammatory area will also be included. Thus representing, in a collaborative environment, the Development Science Department as a member of interdisciplinary project teams. When it comes to the studies performed by vendors, you will be the one to monitor them. In addition, you will provide toxicology interpretation and issue resolution, and participate in various toxicology and R&D initiatives or other active cross-functional collaborations. You will also prepare and review regulatory documentation and represent the organisation in meetings with regulatory authorities.


As this position spans several responsibilities and a high level of interaction throughout the organisation the ideal candidate should first and foremost have a dynamic personality and possess excellent interpersonal skills. Regarding hard skills, this role requires one to have a Toxicology-related degree (p.e. Biomedical Science, pharmacology, etc). Experience-wise this candidate has been active at least ten years in non-clinical development in a multidisciplinary environment (DMPK/clinical pharmacology) focussing primarily on New Chemical Entities, New Biological Entities is regarded a plus. Strong knowledge of the aforementioned TA of Neuroscience (neurodegeneration, neuro-inflammation, epilepsy) is paramount, with pure immunology / inflammatory experience being considered a plus. Bringing in additional experience in regulatory toxicology and GLP compliance in greatly welcomed, as well as experience in new therapeutic modalities such as gene therapy, PROTACs or cell therapy.


The position will allow you to be impactful within Global Drug Development Projects, greatly increasing your network and experience. You will join an environment where you are encouraged to develop yourself further scientifically as well as personally. Besides the opportunity itself you can expect:

  • A competitive salary, starting at 90.000 euros base yearly
  • A considerable secondary package, conform the Belgian system
  • Additional benefits, specific to the company
  • Full support in relocation for you (and your family), if needed


If you are interested in this job, or in similar ones, please feel free to contact me directly.

Martin van der Velden
Principal Associate | Biotechnological and Pharmaceutical Industry

+31(0)23-7548660 / +31(0)6-83656209



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