Principal Scientist Non-Clinical Toxicology - Brussel

Function Group: R&D / Toxicologist


In their continued efforts regarding the discovery and development of groundbreaking medicines and solutions for severe immune system and CNS diseases this organisation is looking for a skilled Toxicologist with experience in Neuroscience. This international organisation (over 8.000 headcount and active in over 40 counties) would ideally like this professional to work in Brussels, but locations in the US and UK will also be considered.


In the role of Toxicologist you will be responsible for the non-clinical development of small molecule, mAB and new modality drug candidates. In this scope you will provide the global project teams with non-clinical support from early research though First in Man, Proof of Concept and further. Thus representing, in a collaborative environment, the Development Science Department as a member of interdisciplinary project teams. When it comes to the studies performed by vendors, you will be the one to monitor them. In addition you will provide toxicology interpretation and issue resolution, and participate in various toxicology and R&D initiatives or other active cross-functional collaborations. You will also prepare and review regulatory documentation and represent the organisation in meetings with regulatory authorities.


As this position spans several responsibilities and a high level of interaction throughout the organisation the ideal candidate should first and foremost have a dynamic personality and possess excellent interpersonal skills. Regarding hard skills, this role requires one to have a Toxicology-related degree (p.e. Biomedical Science, pharmacology, etc). Experience-wise this candidate has been active at least ten years in non-clinical development in a multidisciplinary environment (DMPK/clinical pharmacology) focussing primarily on New Chemical Entities. Strong knowledge of the aforementioned TA of Neuroscience (neurodegeneration, neuro-inflammation, epilepsy) is paramount. Bringing in additional experience in regulatory toxicology and GLP compliance in greatly welcomed, as well as experience in new therapeutic modalities such as gene therapy, PROTACs or cell therapy.


Besides the opportunity to be an integral part in the discovery and development of medicines that will change peoples lives, the organisation:

  • offers a competitive salary
  • a great secondary package
  • additional benefits
  • relocation if needed


If you are interested in this job, or in similar ones, please feel free to contact me directly.

Martin van der Velden
Consultant | Biotechnological and Pharmaceutical Industry


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